Most patients with epilepsy, when treated aggressively, generally do not affect their survival and can survive for a long time, but if they are patients with persistent status epilepticus, their lives may be at risk. Persistent status epilepticus is defined as seizures that do not fully recover consciousness and recur frequently between consecutive seizures, or seizures that last more than 30 minutes and do not stop on their own. It is mostly caused by inappropriate discontinuation of antiepileptic drugs or acute encephalopathy, stroke, encephalitis, trauma, poisoning, etc. Irregular antiepileptic drug treatment, infection, psychiatric factors, overexertion, maternity and alcohol consumption can trigger it. If not rescued in time, there is a high rate of disability and mortality. The treatment of epilepsy requires the correct choice of antiepileptic drugs, the use of reasonable drug doses, close observation of adverse reactions to drugs, and compliance with medical advice to increase or decrease drugs and discontinue them, not to change drug doses or even stop them at will to avoid greater damage.