Leukoaraiosis is an inflammatory systemic disease characterized by recurrent oral and genital ulcers and uveitis. The earliest knowledge of leukoaraiosis began with Hippocrates in the 5th century BC, when there was no good treatment. However, it was not until 1937 that the Turkish dermatologist Behcet first described this type of disease systematically, and it has not been more than 100 years since this type of disease was really understood. Leukoaraiosis is found in East Asia, the Middle East, and the Mediterranean basin, and is commonly referred to as the “Silk Road disease” because of its distribution along the ancient Silk Road. The emergence of leukoaraiosis in life has brought a great impact on the lives of patients, timely treatment is very critical, leukoaraiosis patients should usually understand what are the precautions? A, diet and living: reasonable diet and nutrition, scientific treatment, is an important guarantee to improve the body’s resistance to disease and external harmful factors, but also with drug therapy, slowing down the disease, to promote early recovery of the body can not be ignored important measures, usually should be light and easy to digest food, control the amount of fat intake, pay attention to dietary rules, eat more fresh vegetables and fruits, try to avoid eating The company’s main goal is to provide a good service to its customers. For people with mouth ulcers and intestinal ulcers, avoid eating foods that are too hard or too hot to avoid damaging the trauma, and provide liquid or semi-liquid food for those whose ulcers seriously affect their diet. Maintain a regular diet, a regular life, eliminate bad habits, avoid working late and overworking. Pay attention to hygiene, bathe regularly, change clothes regularly, choose cotton underwear, to avoid stimulation of the skin. Second, the psychological and emotional adjustment: due to the long course of leukoaraiosis, the disease is prone to recurrent attacks and more serious symptoms, patients often appear irritable, anxiety, depression, pessimism and even self-loathing mood, so family members should closely observe the patient’s emotional changes, give patients comfort and understanding, so that patients recognize their own condition, encourage patients to participate in some social activities, eliminate patients a variety of bad mood, relax, keep The family should closely observe the patient’s emotional changes and give him/her comfort and understanding. Third, the disease susceptible parts of the special care: 1, eye damage: the usual eye hygiene, timely treatment of eye diseases, such as photophobia, lacrimation, foreign body sensation and flying mosquitoes, etc., should be less TV, books, pay attention to rest, wear a sun hat or sunglasses. Do not wear contact lenses to prevent corneal ulcers 2, skin damage: skin damage including pustules, folliculitis, boils, erythema multiforme, blisters, cellulitis-like lesions, furunculosis-like moss, erythema nodosum and skin prick reaction. You need to bathe regularly, change clothes regularly, and try to choose some soft underwear to keep your skin clean. Avoid using irritating detergents and avoid squeezing the skin with hands when pustular rash or boils appear. Simultaneous multi-point punctures should be avoided to reduce the needling reaction. 3, oral and vulvar ulcers: usually need to pay attention to oral hygiene, master the correct method of brushing teeth, and develop the habit of brushing teeth in the morning and evening and rinsing mouth after meals. Those with vulvar ulcers should keep their vulva clean, change their underwear daily, and pay attention to the choice of underwear, with high quality cotton material being preferred and often scalded with boiling water, and women should preferably use good performance sanitary napkins during their periods to keep their vulva clean. Like most chronic diseases, the condition of patients with leukoaraiosis may change or recur, and the fight against the disease is destined to be a protracted battle, so a healthy lifestyle and a good state of mind are very important for the treatment of the disease.