Enterocutaneous fistula is an abnormal passage between the intestinal canal and the body surface through which the contents of the intestines flow and is called an extra-intestinal fistula. The mortality rate of enterocutaneous fistula is 5-20%, and the mortality rate of high-grade enterocutaneous fistula is still around 5%, according to the data of Nanjing Military General Hospital, the center of enterocutaneous fistula treatment in China. Simple intestinal fistulas can heal on their own by aspiration and mucosal plugging, but more than 60% of patients require surgery. The symptoms of intestinal fistula The main pathophysiological changes of intestinal fistula are the following: disorders of water-electrolyte and acid-base balance In order to maintain a sustainable volume of body fluids and maintain a stable internal environment the intake and loss of water must be balanced The main source of body water is water in beverages and food; another source is carbohydrates protein and fat The water generated after oxidation in the body surgical inpatients, especially patients with enterocutaneous fistulae, fluid infusion outside the gastrointestinal tract is an important source of water 1. The loss of electrolytes is less frequent and causes less systemic pathophysiological changes. The daily fluid loss in distal ileal fistulas is only about ml and causes less systemic pathophysiological disorders. The loss of acidic gastric juice is likely to produce hypokalemic alkalosis; metabolic alkalosis in patients with intestinal fistula is rare, mainly due to excessive loss of gastric juice and potassium deficiency, which can occur in huge intestinal fistulas in the first two segments of the duodenum, where a large amount of gastric juice is lost. The deficiency can lead to loss of hydrogen ions in the interstitial fluid and can cause metabolic alkalosis if there is also a stimulus for increased sodium reabsorption (e.g., reduced interstitial fluid volume).