When to use granulocyte stimulating factor? 1, chemotherapy and other causes of neutropenia, injection of granulocyte stimulating factor can help prevent the occurrence of neutropenia to reduce the neutrophil. The degree of neutropenia shortens the duration of granulocyte deficiency and accelerates the recovery of granulocyte count, thus reducing the risk of co-infection and fever. 2. Promote the increase of neutrophil count after bone marrow transplantation. 3. Neutropenia caused by bone marrow dysplasia syndrome Neutropenia caused by aplastic anemia Congenital idiopathic neutropenia Myelodysplastic syndrome with neutropenia, etc. What are the possible adverse effects of granulocyte stimulating factor? 1, the musculoskeletal system may sometimes have muscle pain, bone pain, back pain, chest pain (then you can take pain medication). 2, the digestive system may sometimes have a loss of appetite or liver glutathione aminotransferase glutathione aminotransferase elevated. 3.Other people may have fever, headache, weakness and rash with elevated ALPLDH. 4. Very few people will develop shock interstitial pneumonia adult respiratory distress syndrome increased naive cells, etc. Note: The application of granulocyte-stimulating factor does not completely avoid the appearance of granulocytopenia, after the use of granulocyte-stimulating factor, the patient’s white blood cell or granulocyte count may transiently exceed the normal range, and will gradually return to normal after discontinuation of granulocyte-stimulating factor; at the same time, some patients may have their white blood cells and granulocytes reduced to the normal range again after discontinuation of granulocyte-stimulating factor because the bone marrow suppression period has not yet passed. If necessary, granulocyte-stimulating factor therapy should be given again.