What is the genetic component of childbirth in epilepsy

  It is generally believed that epilepsy has some genetic influence. 122 pairs of twins with at least – one epilepsy patient were investigated, of which 44 out of 69 monozygotic twins, both of them suffered from epilepsy, accounting for 63%, and 5 out of 53 dizygotic twins suffered from epilepsy, accounting for 9%. A study of dizygotic twins with epilepsy proved that epilepsy is hereditary; some people investigated epilepsy caused after traumatic brain injury during World War II, the Korean War, and the Vietnam War, and although medical technology has improved rapidly, the incidence of traumatic epilepsy was approximately the same during these periods, thus proving that secondary epilepsy is also hereditary. The magnitude of the genetic effect is related to the etiology of epilepsy. The prevalence of epilepsy in relatives with primary epilepsy is 3% to 4%, whereas in secondary epilepsy it is 0% to 1%, indicating that the genetic influence of primary epilepsy is high, and the closer the blood relationship the higher the prevalence. In addition, if both parents have epilepsy, or if a child has epilepsy, the incidence of epilepsy in the third generation increases to 20%. Therefore, primary epilepsy patients can marry, but should limit their fertility. When choosing a spouse, epileptic patients should be careful not to marry a subject with a history of epilepsy and febrile convulsions in the family or in themselves, and should not marry a person with close blood ties. By primary epilepsy, we mean that the onset is under 25 years of age, the seizure form is grand mal or petit mal, there is no limited brain damage on brain map and neurological examination, and no clear cause has been found.