Reflux esophagitis may cause symptoms of vomiting blood, which is a complication of reflux esophagitis but is relatively rare. When patients with reflux esophagitis develop inflammation, erosion, and ulceration of the esophageal mucosa, it can lead to upper gastrointestinal bleeding. However, most patients vomit blood because of bleeding due to peptic ulcer, or bleeding due to pancreatic esophageal mucosal tear syndrome, and possibly acute erosive hemorrhagic gastritis, and bleeding due to ruptured esophagogastric fundic varices. Regardless of the cause, if a patient has symptoms of vomiting blood or presents with abdominal pain or black stool he or she needs to go to the hospital promptly and cooperate with the doctor to improve the relevant tests to assist in making a clear diagnosis. If the presence of upper gastrointestinal bleeding is confirmed, it is necessary to cooperate with the doctor to give hospitalization and symptomatic supportive treatment such as acid suppression, hemostasis, blood transfusion and fluid replacement.