Syphilis is a chronic infectious disease caused by the syphilis spirochete. It is mainly transmitted through sexual intercourse, and rarely through kissing, breastfeeding, and contact with the daily products of patients with infectious damage. The main purpose of this article is to provide information about the use of the Internet for the purpose of the Internet. The most common type of chancre is the syphilis spirochete test. The most common types of chancre in men are around the glans, coronal sulcus and ties, and in women, the labia, clitoris, urethra and mons pubis, especially the cervix. It is easy to be diagnosed. The main manifestation of second stage syphilis is syphilis rash, which can be confused with other skin diseases and lead to misdiagnosis, and usually occurs 3-4 weeks after the hard chancre subsides. In addition to skin damage, syphilis can also invade the internal organs, nervous system and mucous membranes, and there are a large number of syphilis spirochetes on the surface of mucous membrane white spots, which is an important source of infection. Stage 3 syphilis generally occurs 3-5 years after infection with syphilis and can be as long as 20-30 years, mainly due to untreated or inadequate treatment time, inadequate measurement of medication, or low immune function. Stage 3 syphilis can involve mucous membranes, nodular rash or dendritic swelling occurs, most mainly causing damage to the nervous system, heart, bone and joint, eye syphilis and internal organs, which seriously affects a person’s normal life and work, and can cause disability in severe cases. There is also type 2 syphilis which is more common: 4. Invisible syphilis This is the most common type of syphilis in clinical practice, where patients do not show any symptoms, but only have syphilis spirochetes in their blood, which are often found during medical examinations. Because of the absence of any clinical manifestations is often overlooked, often found only when the patient appears visceral damage, but by then it is too late, visceral damage is often irreversible. 5, syphilis in pregnancy The mother with syphilis can transmit it to the fetus through the placenta, causing intrauterine infection in the fetus, which mostly occurs after the fourth month of pregnancy, resulting in miscarriage, premature birth, stillbirth or delivery of a fetus transmitted syphilis child. Therefore, early diagnosis of syphilis and early treatment are very important. We say that when diagnosing skin diseases, it is very important to take a detailed history, the doctor has to look at the rash, to touch the rash, and to make a clear diagnosis in order to prescribe the right medicine for a good cure. What we call a miracle doctor is actually asking the medical history carefully, observing the rash carefully, doing the appropriate examination and using the right medicine for the right condition.