(1) Age: Most commonly seen in middle-aged and elderly people over 40 years of age. (2) Sex: The disease is more common in men, with a male to female ratio of 2:1, and often in women after menopause. (3) Hyperlipidemia. (4) Hypertension. (5) Smoking. (6) Diabetes mellitus. (7) Obesity. (8) Occupation: Jobs with little physical activity and intense mental activity, often with a sense of urgency, are prone to this disease. (9) Diet: If you eat a high-calorie diet for a long time, it can cause dyslipidemia, obesity, hypertension and diabetes and lead to this disease. (10) Heredity. (11) Other: imbalance of micronutrient intake, type A personality (impulsive, competitive, often feel that time is not enough); deficiency of O
(12) Other: imbalance in the intake of micronutrients, type A personality (impulsive, competitive, and often feeling short of time); O deficiency, VitC deficiency, and reduced activity of enzymes in the arterial wall, which can increase vascular permeability, are thought to predispose to the disease.