Esophageal cancer is a kind of digestive malignant tumor common in Chaoshan area, with the age of onset mostly above 40 years old, and the main symptom is progressive dysphagia. The main symptom is progressive dysphagia. Early and middle stage esophageal cancer should be treated by surgery. Traditional surgical methods for esophageal cancer mainly include left open thoracotomy with single incision, right open thoracotomy with two incisions or three incisions, which are traumatizing and have a greater impact on the cardiopulmonary function of patients, with many complications and slow postoperative recovery. In recent years, the Department of Cardiothoracic Surgery of our hospital has made significant progress by carrying out combined minimally invasive thoracolaparoscopic surgery for the radical treatment of esophageal cancer. The surgery of esophageal cancer can be completed through several small holes in the chest and abdomen. In this method, four 1-2 cm holes are taken in the chest and five 1 cm holes are taken in the abdomen (the length of incision of traditional open thoracic surgery is 20-30 cm), and luminal instruments are inserted to carry out esophageal and gastric dissection, lymph node dissection, and digestive tract reconstruction surgery. Compared with conventional open-heart surgery, the advantages of this technique include less impact on the chest and abdominal organs, less surgical trauma, significant reduction of postoperative patient pain, greatly reduced postoperative complications, faster recovery, and significantly shorter hospitalization time. Thoracic laparoscopic combined minimally invasive radical esophageal cancer surgery can avoid the trauma caused by open chest and the resulting postoperative complications, and it strives for the opportunity of surgical radical resection for patients with esophageal cancer who have pulmonary insufficiency and can’t tolerate open chest surgery.