Clinical features The incidence of pediatric respiratory tract infections is still quite high this winter, especially in the past January, there is a rapid epidemic trend of patients with high fever, outbreaks in kindergartens and elementary school, with rapid onset, temperature above 39 degrees, lasting 5-7 days, accompanied by cough, headache, some manifestations of tonsillar enlargement, and some have lung inflammation. Ancillary tests: Blood tests showed elevated white blood cells and neutrophils, elevated ultrasensitive CRp, and some children were positive for Mycoplasma pneumoniae. Respiratory viral testing for influenza virus is very low. Adenovirus was partially detected. Treatment experience: In the past, 90% of the children’s body temperature returned to normal after 3 days of cephalosporins plus azithromycin, but not this year, the temperature was still above 39 degrees at the follow-up visit after 3 days, and oral oseltamivir phosphate did not help. If cephalexin plus azithromycin is added along with acyclovir in the sedative drip, the fever mostly subsides within 48 hours.