Diabetic patients with a hole in the ankle can get better, but need to be standardized treatment under the guidance of clinicians, the specific treatment plan includes controlling blood glucose, nutritive nerves and infection control. 1. Blood sugar control: first of all, you need to control blood sugar through medication, generally can apply hypoglycemic drugs, such as metformin, etc.; you can also apply insulin subcutaneous injection therapy, especially for the people who have poor glycemic control effect with medication. 2. Nutritional nerve: diabetic patients with symptoms and nerve damage is also related to the application of nutritional nerve drugs, such as methylcobalamin. 3. Control infection: after determining the specific type of infection, you can regularly apply anti-inflammatory drugs, such as cefixime and so on. After the diabetic patient has a hole in his ankle, he should go to the hospital in time, and under the guidance of the clinician for standardized treatment, he can gradually recover.