Pancreatic tumor size has a certain relationship with the degree of malignancy, but the degree of malignancy also needs to be combined with pathological staging, metastasis and other comprehensive consideration. Pancreatic cancer is a kind of digestive tract malignant tumor with insidious onset, rapid progression, extremely poor treatment effect and prognosis. For pancreatic malignant tumors with the same pathological staging, the larger the diameter of the tumor, the larger the stage of the tumor may be, and the greater the likelihood of distant metastasis and the greater the degree of malignancy may be compared to tumors with small stages. However, the degree of infiltration of the tumor, metastasis, etc. will also affect the staging. For different types of pancreatic tumors, the comparison of benignity and malignancy needs to be determined according to the results of pathological examination. Common malignant tumors include pancreatic cancer, ductal adenocarcinoma, etc., whose degree of malignancy is greater than that of benign tumors such as cystic tumors, lipomas and fibrous tumors. The degree of differentiation of the tumor cells should also be considered. The lower the degree of differentiation, the higher the degree of malignancy. If pancreatic cancer is suspected or diagnosed, it is recommended to go to a regular hospital for a comprehensive assessment of the condition and follow the doctor’s instructions for treatment, so as to avoid delaying the condition.