When patients have symptoms of fire such as dry mouth, sore throat, constipation, etc., they will think of taking some agents with the effect of clearing heat and detoxifying and removing fire, commonly used drugs include Niuhuang detoxification tablets, Huang Lian Shangqing Pills, San Huang Tablets, Yin Qiao detoxification tablets, etc.. But in Chinese medicine, fire can be divided into liver fire, heart fire, etc., and generally need to correspond with the medication. The effect of any drug varies from person to person, so the clinician needs to choose the right drug combination according to the patient’s condition. 1. liver fire: in Chinese medicine, the common clinical symptoms of liver fire are dizziness and tinnitus, dry eyes and red face, yellow urine, etc. Commonly used drugs are mulberry leaf, chrysanthemum, peppermint, forsythia, yellow forsythia, etc.; 2. heart fire: heart fire in Chinese medicine, often manifested as insomnia and agitation, dry mouth and desire to drink, constipation, etc. Constipation and so on, gardenia, raw earth yellow, mulberry leaf, maitong, Wu Wei Zi, bamboo leaf and other Chinese medicine in the clinical more commonly used; 3, stomach fire: stomach fire often have gum bleeding, pulse speed up, bad breath and other performance. The common symptoms of kidney fire are insomnia and sleeplessness, weakness and night sweats, etc. Commonly used medicines include rhubarb and heliotrope, which can clear heat and detoxify and remove fire. In addition, there are some contraindications to the use of each drug, it is recommended to carefully describe the symptoms to the doctor, by the doctor’s diagnosis and treatment, do not self-dispensing, taking drugs to avoid adverse consequences.