Also known as infantile roseola, the disease does not provide lifelong immunity after one occurrence, so it can still occur a second time. The cause of infantile rash is not known and may be related to human herpesvirus type 6 infection. It is common in children under 2 years old, manifesting as persistent high fever for 3~5 days, which may be accompanied by convulsions and pharyngeal hemorrhage. After the fever subsides, a dense pink maculopapular rash appears all over the body without flaking, which may be accompanied by enlarged superficial lymph nodes in the head and neck and mild diarrhea, and there is no hyperpigmentation left after the rash subsides. As it is not a contagious disease, it does not produce protective antibodies and therefore is not a lifelong immunity, so it is still possible to get sick for a second time. Parents are advised to bring children suspected of having infantile emergency rash to the dermatology or pediatrics department of a regular hospital in a timely manner for symptomatic treatment under the guidance of a doctor, and to pay attention to the children’s diet, drink more water and strengthen their resistance.