Cirrhosis is mostly a late manifestation in patients with chronic hepatitis, and long-term alcohol abuse can also lead to cirrhosis. Due to cirrhosis of the liver, the blood return to the spleen is blocked, resulting in stasis of blood in the spleen, causing the spleen to gradually increase in size, from the size of a fist at first, to a basketball-like size. The normal physiological function of the spleen is to remove senescent blood cells from the blood, but when the spleen enlarges, its physiological function becomes hyperactive, and it excessively destroys blood cells, and in addition to removing senescent blood cells, it also destroys and removes non-senescent blood cells as well. As a result, when the spleen is enlarged, patients often experience a decrease in white blood cells, red blood cells and platelets. The decrease in white blood cells leads to a decrease in the patient’s body resistance; the decrease in red blood cells leads to anemia and general weakness; the decrease in platelets leads to easy bleeding, and severe bleeding can be life-threatening. When hypersplenism is not present, no special treatment is needed. When hypersplenism is present, immediate treatment is required. There are two main treatment methods: 1. Interventional treatment, i.e. splenic artery embolization. The advantage of this method is that it does not require an incision, but the disadvantage is that the long-term outcome is not good. 2.Surgical removal of the spleen. Removal of the spleen is the most effective treatment for hypersplenism, and the patient’s white blood cells and platelets can return to normal 48 hours after the removal of the spleen. However, traditional surgery is very traumatic, prone to complications such as liver failure after surgery and slow recovery. At present, the best surgical method is minimally invasive surgery, i.e. laparoscopic removal of the spleen, which is less traumatic and has a faster postoperative recovery. However, this method is technically difficult, especially the removal of large spleen, and only a few hospitals in China are currently carrying out this technique.