(1) Most malignant tumors in children originate from embryonic mesoderm and are mostly sarcomas, while in adults, they are mostly epithelial in origin and are mostly carcinomas; (2) Children, especially younger children, are often unable to express the discomfort caused by the disease correctly, which makes the early detection of tumors difficult, so the diagnosis is more likely to be made in the middle and late stages; (3) Sarcomas are highly malignant and progress rapidly, but fortunately, they are more sensitive to treatment (including drug therapy and radiation therapy) than adults; (4) Because children’s tumors grow rapidly and are sensitive to treatment, the treatment effect is significantly better than adults. (4) Because children’s tumors are fast growing and sensitive to treatment, the treatment effect is significantly better than that of adults. The overall cure rate of childhood cancer can be more than 60%, while the cure rate of adult cancer is still less than 50%. (5) While treating tumors, we should also pay attention to the growth and developmental characteristics of children and try to ensure the normal function of all organs of children.