Epilepsy is a neurological disorder with recurrent clinical seizures and a long course, which seriously threatens the physical and mental health and quality of life of patients, often affecting their education and future work, and bringing a serious burden to families in terms of life and finances. Nowadays, 70% of epilepsy patients can have their seizures controlled by medication, but about 30% of patients become drug-refractory epilepsy. The current view is that drug treatment for 2-3 years is ineffective (epilepsy department of regular hospital, clear diagnosis and epilepsy typing, regular drug treatment) is drug refractory epilepsy. As functional neurosurgery techniques continue to develop, surgery may be the best approach for this group of patients. After a professional preoperative evaluation, if the epileptogenic zone can be identified and it can be safely removed, the expected outcome is very good. The procedure of preoperative evaluation includes: 1. Confirmation that the patient has drug-refractory epilepsy. 2. Evaluate the efficacy of the proposed surgery. 3. Assessment of the patient’s postoperative quality of life. 4. Assessment of the timing of surgery. 5. Assessment of the epileptogenic zone: this is the most important. 6. Assessment of surgical risk. The assessment of epilepsy surgery is laborious and the most time-consuming is the video EEG monitoring, which should monitor the patient’s natural seizures many times, fully understand the patient’s seizure performance and complete EEG information, get the first-hand information that the doctor needs, then combine the imaging data and neuropsychological assessment, and after careful analysis, clarify the epileptogenic zone. After the epileptogenic zone is found, the relationship between it and functional areas has to be evaluated, whether it can be safely removed …… etc. All these need to be evaluated by professional doctors in professional institutions. Therefore, patients and families should have patience and perseverance, it is different from other surgeries. Although the surgical resection of epilepsy is important, what is more important is the long preoperative evaluation process, the positioning is precise, the surgical result is good.