Diabetic itchy red legs need to be under the guidance of a doctor to clarify the cause of the disease, if the local infection or allergies and other reasons, you can follow the doctor’s instructions for external application of mupirocin ointment or take loratadine and other drugs to treat. 1. Local infection: diabetic patients are prone to various infections, when bacterial infection occurs in the calf, the inflammation stimulation can cause local redness, itching symptoms. You can use topical mupirocin ointment and other treatments as prescribed by the doctor while controlling blood sugar. 3. Allergy: diabetic patients calf skin contact with allergic substances, can cause allergic dermatitis, resulting in localized itching and redness of the skin. You can take antihistamine drugs such as loratadine orally as prescribed by the doctor. Diabetic calf itchy red piece should go to the hospital in time to improve the examination, under the guidance of the doctor’s treatment.