Platelets are a tangible component of the blood that can release substances that promote vasoconstriction and blood clotting. High platelet count may be related to primary thrombocytosis, reactive thrombocytosis, the reasons are analyzed as follows: a. Primary thrombocytosis: primary thrombocytosis is a chronic myeloproliferative disease characterized by continuous proliferation of bone marrow megakaryocytes or thrombocytosis, etc., common true erythropoiesis, myelodysplastic syndrome, chronic granulocytic leukemia, etc., mostly manifested as bleeding, thrombosis, spleen enlargement, etc., when myelosuppressive drugs can be applied to reduce the number of platelets, anti-platelet drugs, and prevent thrombosis. Second, reactive thrombocytosis: 1, acute blood loss: acute massive blood loss, the body’s hemostatic mechanism will be rapidly activated, platelets will be elevated, which in turn leads to a high platelet count. At this time, the bleeding should be stopped quickly to avoid hemorrhagic shock. 2. Acute hemolysis: When patients have acute hemolysis, the platelet count in the bone marrow will be elevated for a short time due to the negative feedback principle of the body. Usually when the hemolysis reaction is controlled, the platelet count will gradually return to normal; 3, acute inflammation: for patients with acute cholecystitis, acute appendicitis and other diseases, the influence of inflammatory stimulation may lead to elevated platelets, this situation generally first control the inflammation, after the inflammation subsides, the platelet count can gradually return to normal; 4, splenectomy: after splenectomy will lead to platelet Short-term elevation, generally do not deal with, and then slowly return to normal, if platelets are too high, you can use aspirin to antagonize platelet function. Platelets are commonly used to stop bleeding and to diagnose thrombotic disorders. When the body has bleeding wounds, platelets can play a role in stopping bleeding, but a high platelet count may cause the blood in the blood vessels to clot and form a blood clot. Therefore, when a patient has an elevated platelet count, the cause should be identified and treated immediately.