1. Palpitations, cold sweats, and temporary deficiency. Mainly due to the patient’s lack of understanding of the laser, mental tension, accounting for about 60%. Preventive measures: stabilize the patient’s emotions before treatment, correct guidance, to relieve concerns. 2, local pain. CO2 laser treatment has a certain degree of skin stimulation, causing local pain, if the lesion range is more than 0.2 cm2, generally before the operation can be used 1% lidocaine local infiltration anesthesia; lesion range is less than 0.2 cm2, the general pain can be tolerated. 3, accidental injury to normal tissue. The operator is required to operate skillfully, accurately grasp the striking energy and irradiation mode and time, and cover the normal tissue around the lesion with saline gauze. Pay attention to the treatment rather shallow than deep, rather small than large. 4, trauma infection. Although it is an isolated phenomenon, it should be taken seriously. Routine disinfection before surgery, pay attention to aseptic operation, postoperative antibiotics can be applied appropriately. 5, traumatic bleeding. It is less common, but cannot be ignored. Check the vascular route before surgery, operate gently and stop bleeding in time, and instruct the patient not to tear off the scab by himself after surgery. 6. Postoperative scar. If the lesion is large and deep, it is easy to leave a scar at one time, especially on the face and parts affecting the beauty. It can be treated in stages and phases. The new tissues after CO2 laser treatment are sensitive to ultraviolet light and are prone to hyperpigmentation. 8.Visual impairment. The laser beam for a long time will damage the cylindrical visual cells in the central macular recess, which will reduce the visual acuity and affect the dark vision. Therefore, both the operator and the patient should wear protective eyewear during the operation, and ensure that there is sufficient brightness in the room to narrow the pupil and reduce the amount of laser light entering the eye. 9, cough. CO2 laser cauterization lesions produce irritating odor, causing coughing, should strengthen the studio smoking exhaust measures. 10, dizziness and discomfort. Often caused by indoor air pollution. Laser room should be kept air circulation, regular disinfection, reduce the entry and exit of idle people. Continuous work should not exceed 1 hour, otherwise rest for a moment before continuing treatment.