The maintenance effect of the sealant injection is usually about 3-6 months. Sealant injection is an injection of long-acting hormones and local anesthetic drugs into the painful local area, which can play an anti-inflammatory and pain-relieving role. Usually, the duration that can last for about 3 months with one closure treatment. Generally, only one closure injection is performed in the same area within 6 months in principle, which can provide good relief because of the long-acting hormone. For patients with local soft tissue injury or muscle pain and other chronic diseases, the effect is more ideal. But the closed injection also has certain contraindications, the existence of skin damage infection or diabetes patients can not perform closed injection. During the closure treatment, patients need to pay attention to avoid heavy physical work, avoid a posture for too long, pay attention to the local warmth, if necessary, you can follow the doctor’s instructions oral blood pain medication.