Preoperative routine examinations: routine blood, urine, feces, ECG, ultrasound, mammogram, chest X-ray, liver and kidney function tests, tumor markers, etc. The main purpose of the examination: to assess the patient’s tolerance to surgery and to use it for later follow-up observation and comparison. Examination time: one day before surgery. Pre-operative preparation: One day before surgery, nurses provide pre-operative instructions and pre-operative skin preparation to patients. Breast surgery is aseptic and skin preparation is mandatory, mainly the skin in the preoperative surgical area needs to be shaved (mainly axillary hair). Postoperative diet: After radical breast cancer surgery, the surgical wound is large, there is a lot of blood and fluid leakage, and the consumption of body fluids is also large. Therefore, proper attention should be paid to the postoperative diet, which should be easily digestible and high in protein plus rich in vitamins, and it is recommended to consume fish, lean meat, etc., as well as a variety of vegetables and fruits, so that the body can recover physically as soon as possible to promote wound healing and be able to tolerate postoperative adjuvant therapy. The significance of drainage tube and the key points of nursing care: Because of the large invasive surface of breast cancer surgery, lymphatic fluid, exudate and blood leakage can accumulate under the skin after surgery, causing fluid accumulation and making the flap unable to adhere to the invasive surface. The purpose of drainage tube drainage is to keep the flap close to the wound surface, which is conducive to wound healing and prevents necrosis and infection of the flap. Postoperative care should be taken to prevent pressure, distortion and excessive stretching of the drainage tube. Special attention should be paid to keep the upper limb of the affected side braked for 1-3 days after surgery. Postoperative protection of the affected limb: (1) no blood sampling or intravenous injection in the affected limb; (2) no heavy lifting of the affected limb; (3) avoid skin breakage and infection of the affected limb; (4) avoid mosquito bites; (5) avoid shaking hands. Mainly due to postoperative lymph node dissection, lymphatic vessels are broken, so that lymphatic return is blocked, and postoperative edema of the affected limb is easy to be combined with lymphangitis if not handled properly.