Mean platelet volume is the average value of platelet volume. It is mainly used clinically to observe the presence of bleeding tendency and changes in bone marrow hematopoietic function, as well as for the diagnosis and treatment of some diseases. The normal value of mean platelet volume is 7-11fl. When the mean platelet volume is outside the normal range, it is called high mean platelet volume. The clinical condition of a patient is usually determined by the platelet count (PLT) together with the mean platelet volume parameter (MPV).1. High MPV with normal PLT: common in chronic myeloid leukemia, myelofibrosis, splenectomy, and some alpha and beta thalassemia.2. High MPV with reduced PLT: common in acute myocarditis, cardiogenic hypertrophic osteoarthropathy, preeclampsia, immune thrombocytopenic purpura, and diabetes mellitus; 3. High MPV and elevated PLT: common in chronic granulocytic leukemia, splenectomy, and reactive thrombocythemia and iron deficiency. If the mean platelet volume is only slightly high, it can be observed for a few days and then rechecked. It is possible that the temporary blood concentration is caused by low water intake and high exercise, and the blood test will be repeated in a week to check the values of white blood cells, platelets and mean platelet volume. If the results are normal, no special treatment is needed. If the results are abnormal, you should go to the hematology department of the hospital as soon as possible to clarify the cause and treat the cause.