The course of epilepsy treatment is long, and it is common to encounter concurrent illnesses such as colds, fever, diarrhea, and vomiting. At this point, some parents mistakenly believe that antiepileptic drugs should be discontinued. In fact, this is very dangerous because fever, cold, vomiting and diarrhea are most likely to induce seizures when they occur, and if the medication is discontinued at this time, there is a high possibility of seizures and even persistent status epilepticus. On the contrary, not only should you not stop the medication, but you should also increase the dosage if you have vomiting, diarrhea, fever, which affects the absorption or accelerates the metabolism of the medication, and you should also use medication for other diseases such as cold and flu at the same time. The antiepileptic drug efficacy should be avoided due to drug interactions.