Pathogenesis of essential hypertension

  The pathogenesis of primary hypertension: 1, genetic. Patients with a genetic background account for 30% – 50% of the hypertensive population, 2, neuropsychiatric effects. Patients in long-term tension, anxiety, irritability and other emotional changes and often in a state of stress, engaged in work that requires a high degree of concentration, can induce the emergence of hypertension. Sympathetic excitation can also induce the emergence of hypertension.  3, renin angiotensin aldosterone system balance imbalance.  4, metabolic syndrome. 50% of hypertensive patients have insulin resistance. Hyperlipidemia, obese patients are prone to hypertension.  5, too much sodium. That is, excessive salt intake.  6, obesity. Obesity is a component of the metabolic syndrome, often accompanied by insulin resistance, hyperinsulinemia, increased sympathetic system activity, and fat cells produce too much angiotensin, etc., may be the cause of their hypertension.  7, smoking, excessive alcohol consumption can also cause hypertension.