In my daily clinical work, I am often asked by patients: Is it necessary to change the antihypertensive drugs frequently to prevent drug resistance? What are the side effects or hazards of taking antihypertensive drugs? My blood pressure was well controlled at the beginning, but after a few years, my blood pressure has increased again. Can I stop taking the medication when my blood pressure is normal? Now on the common misconceptions in the treatment of hypertension to do a answer: First, the vast majority of hypertension is now primary, once diagnosed, usually require long-term adherence to medication. In other words, it is necessary to take medication every day, month after month, year after year. The medication is not enough, you must take the right drug. Some patients often say I take antihypertensive drugs, but when asked carefully, he did not use the right drugs, and therefore poor blood pressure control. Do not take medication irregularly, eat eat stop. Secondly, there is no problem of drug resistance in the treatment of hypertension. Unlike our antibiotics, antihypertensive drugs are prone to drug resistance once abused. The treatment of hypertension is individualized and each person’s situation is not necessarily the same, thus the response during medication is also different. The key problem why we think that antihypertensive drugs are resistant is that the right antihypertensive drug is not chosen. Third, the side effects of antihypertensive drugs are relatively few. The most common side effect of the angiotensin-converting enzyme inhibitor (ACEI) class is a dry cough, which can occur within a few days or months after taking the drug. The cough is irritating and can occur during the day and night, especially if it occurs after a few months of taking the drug, and is easily misdiagnosed. Angiotensin II receptor antagonists (ARBs) do not have this side effect. The most common side effect of beta-blockers is weakness, which is characterized by a lack of ability to lift the feet, especially when going upstairs. This side effect is temporary and usually reduces or disappears significantly after taking them for a period of time and does not affect daily life and work. The common side effects of diuretics are electrolyte imbalance, weakness, and gout triggering. The common side effects of calcium antagonists (CCB) are dizziness, headache, redness, and edema of both lower limbs. Fourth, antihypertensive drugs are usually safe. There is a classic saying: There is no safe drug, only safe physicians. The fear of the danger of antihypertensive drugs may come from many irresponsible advertising campaigns nowadays. In fact, it is very safe to lower blood pressure effectively; on the contrary, excessive blood pressure is the real unsafe factor. Only standardized and regular use of antihypertensive drugs, lowering blood pressure control within the normal range and reducing the dramatic fluctuations of blood pressure can effectively reduce the incidence of cardiovascular and cerebrovascular disease events, improve the quality of life of patients and extend life expectancy, which is the safest. Fifth, why does blood pressure start to be well controlled and then start to rise again a few years later? This may be something that many physicians are not aware of. In fact, as age increases, blood pressure rises as blood vessels become atherosclerotic and less elastic, which is why hypertension occurs mostly in the elderly (except for genetic factors). Since blood pressure increases with age, so do patients with hypertension. After taking it at first, blood pressure is well controlled, but after a few years, blood pressure will still rise and may not be effectively controlled by the original drug. Sixth, can hypertensive patients stop taking their medication after their blood pressure has dropped to normal after treatment? For the majority of patients, the medication cannot be stopped. But everyone’s blood pressure fluctuation is regular, this law includes the daily pattern of day and night, monthly pattern, the law of each season, as long as we pay attention to observation, find their own blood pressure change pattern, completely according to their blood pressure situation appropriate adjustment of the dosage of antihypertensive drugs. Seventh, patients with hypertension also need to exercise properly. Once some patients know they have hypertension, they are afraid to do exercise. In fact, as long as you do not do exercise when your blood pressure is very high, proper exercise can lower your blood pressure. Suitable exercises for hypertensive patients include walking, tai chi, jogging and other aerobic exercises. Hypertensive disease is a common disease in cardiovascular medicine, multi-morbidity, there are many methods of treatment, but no matter what treatment is used, it is necessary to bring the blood pressure up to standard. At present, the awareness rate, treatment rate and control rate of hypertension in China are very low. As a cardiologist, it is our duty to improve the awareness rate, treatment rate and control rate of hypertension. We hope that through the above Q&A, we can eliminate the misunderstanding of the majority of patients with hypertension and choose the antihypertensive drugs reasonably and correctly, so that we can really control blood pressure effectively and enjoy a good life.