Pituitary tumor surgery may affect sexual function. The pituitary tumor growth site is located in the saddle area, and the pituitary gland itself is an endocrine organ. Generally pituitary gland is divided into anterior and posterior pituitary gland, which secrete nine hormones respectively, and the nine hormones include sex hormones. Pituitary tumor surgery, whether open or transnasal butterfly, is performed in the pituitary area, which will most likely affect the secretion of hormones by the pituitary gland, including sex hormones. If the tumor is small and the pituitary gland is less damaged during the surgery, the secretion of pituitary hormones, including sex hormones, will not be affected in this case and thus will have less impact on sexual function. If the tumor is larger, the pituitary gland is more involved in the operation and more damage is done to the pituitary stalk and pituitary gland, the sexual function of the patient may be affected to some extent, mainly because the secretion function of the pituitary gland is affected to some extent. However, with the development of minimally invasive technology, the development of minimally invasive endoscopic technology and the progress of equipment, including close observation and multi-angle observation, the interference with the pituitary gland is getting smaller and smaller, and the progress of surgical methods has less and less influence on the pituitary gland, so the influence on the endocrine function and sexual function of the pituitary gland is gradually reduced. In conclusion, depending on the situation, the sexual function of the patient may be affected to different degrees, and advances in surgical techniques and methods have brought greater benefits to patients.