1. Cervical and lumbar spondylosis and osteoarthritis pain: cervical spondylosis, cervical disc herniation, costochondritis, lumbar disc herniation, coccygeal pain, knee arthritis, heel pain, temporomandibular joint dysfunction syndrome, degenerative osteoarthritis, gouty arthritis, pain syndrome after cervical and lumbar spine surgery. 2. Headache: cervicogenic headache, migraine, post-traumatic headache and various intractable headaches. 3. Neuralgia: trigeminal neuralgia, brachial plexus neuralgia, intercostal neuralgia, sciatica, acute herpes zoster, post-herpetic pain, pain after nerve injury, phantom limb pain, stump pain, diabetic neuralgia, complex local pain syndrome. 4. Soft tissue pain: acute and chronic lumbar sprain, lumbar muscle strain, supraspinous interspinous ligamentitis, lumbar dorsal myofasciitis, fibromyalgia syndrome, tenosynovitis, frozen shoulder, tennis elbow, soft tissue injury. 5, visceral pain: intractable angina pectoris, myocardial infarction, chronic pelvic inflammatory disease, abdominal plexus pain. 6. Ischemic pain: Raynaud’s disease, occlusive thrombotic vasculitis, thrombophlebitis, erythema limbica, reflex sympathetic dystrophy, etc. 7. Cancer pain and pain caused by benign tumor, recurrence and metastatic pain after cancer surgery. 8. Dysmenorrhea, chronic pelvic pain, menopausal syndrome. 9. Non-painful diseases: intractable eruption (diaphragm beating), acute facial neuritis (facial palsy), facial muscle spasm, sudden deafness, tendon sheath cyst, liver and kidney cyst. Neurodermatitis, sudden deafness, inner ear dizziness, gout, scar pain, facial muscle spasm, eyelid spasm. 10, various chronic, complex, etiologically difficult to diagnose intractable pain.