1, the right way to seek heirs is to nourish the essence Yue’s great emphasis on the decisive role of nourishing the essence to seek heirs. He advocates that if a man “can keep the innate spirit (essence), he will be more than halfway to the way of seeking a son”. In the area of life and living, it is proposed that: “less desire” to gather essence, “moderate labor” to cherish essence, “punish anger” to hide essence, “abstain from drunkenness” to protect essence, and “protect the essence”. “The right way to seek healing is to protect the essence and to be careful with the taste. In practicing sperm, it is suggested that at midnight, at midnight, sit down with your clothes on, rub your hands together and put your right hand around your outer kidney, and cover your navel with your left hand and concentrate on your inner kidney for about half an hour, and practice it for a long time, and sperm will flourish. In the attached seed formulas, each of the 30 internal formulas are mainly based on kidney tonics and essence fillers. (12), bone flesh (11), ginseng (11), asparagus (10), cypress seeds (10), etc. The majority of these drugs are mainly used to tonify the kidneys and benefit the essence. Finally, people are cautioned: “to seek the next regimen, the gentleman think twice, …… to maintain the essence of the yuan, to borrow the power of medicine. If you rely on the power of medicine and waste the essence, refining stones to make up for the sky, it has help?” Yue pointed out that the key to taking the seeds of medicine is to select the right prescription, in order to achieve the desired effect. Therefore, “specially written experience good prescription, and discretionary warm and cool tonic diarrhea of the agent, the deficiency of the actual cold and heat of the examination of the case, so as to help one of the wide heir. And stressed: “Although the prescriptions listed are not one, the effect is not in both. Or the good worker to check the pulse and vainly examine the evidence, or the patient knows the cold and the heat of the patient and the selection of the prescription.” From the listed cases, such as case 1, a strong man without children, Yue’s patient “six pulse flooding, heavy pressure on the weak” concluded that the heart fire is overwhelming, the phase fire incites from, and the kidney water is not enough to control it; usually also addicted to alcohol and like to bo, excessive room. After half a month of treatment, he took one ingredient of Zhonghe Seed Pill, and three months later, he took another ingredient of Zhonghe Seed Pill, and became pregnant six months later. As Yue said, “The doctor has his own specimen and his own sequence of medicine to detect the disease. Such as detoxification of the muscle and other agents, is not the seed medicine? If you do not apply the order, that is, a large temperature, the big tonic, it is difficult to see the effect. This is an example to the rest, the sick doctor, all should be touched and by-pass can also be”; “where the formula is not seed, and used to become the seed of the work of the cover of the military and civilian, the work does not cover, and its determination of peace a.”. Therefore, the key to seeds is to select the prescription for the evidence and use the medicine. From the above example, we can also appreciate Yue’s seed idea of seeking heirs first, first to remove the evil to get rid of the weeds, and then support the righteous to breed good seeds, the evil to go is safe, the seeds are easy to conceive. 3, the seed of sperm first spleen “Su Wen? The “Yin and Yang should be like the great theory” cloud: “gas to the essence, the essence of the return to the transformation.” The spleen is the essence of the latter, the main transport and transformation of water and grain essence, the source of biochemical energy and blood. If the spleen and stomach are healthy, the qi and blood will be full, and there will be a source of essence, and the seeds will be expected. If the body is deficient in essence, it is difficult to have children, so Yue believes that the first thing to do is to take care of Zhongzhou. The spleen and the stomach are healthy, the latter is benefited, the water and grain essence can be gathered to the kidneys, the essence is strong, the son is strong. For example, case 3, forty years old and childless, weak, six veins, two feet like silk, a seemingly extinct, although the evidence is undoubtedly a deficiency of kidney essence, but a long time to take Zhiyin Dihuang Pills, eight flavor Dihuang Pills are not effective. The evidence is undoubtedly a deficiency of kidney essence, but the long-standing use of Zhiyin Dihuang Wan and Ba Wei Dihuang Wan is not effective. The patient was treated with tonic Zhong Yi Qi Tang plus Sha Ren and Shen Qu, and when the spleen and stomach were healthy, the patient was treated with Bawei Dihuang Wan and He Che Seed Pill and got a child. He was impotent and had no son, and his six veins were extremely weak. Yue first warmed the spleen to stop the bleeding, and then used the pill formula (ginger thickened park, atractylodes, Shen Qu, malt, Wu Wei Zi), five powder cake (gorgonian, poria, yam, lotus meat, coix seed), tonifying Zhong Yi Qi Tang with Fructus Lycii and Duzhong, and Bajhen Tang with Fructus Lycii and Duzhong to regulate the spleen and stomach, and finally took Ju Jing Wan to obtain a son. In case 6, she had been infertile for 3 years, with a weak pulse at the right side of the gateway and a slippery pulse at the left side of the foot. Yue’s opinion is that “this is because the spleen deficiency can not control water, resulting in kidney deficiency can not animal sperm …… treatment should be real spleen nourishing the kidney, the earth is strong, water from the collection, the kidney is full of sperm from the thick, the birth of a child can be sure.” So with the Four Gentlemen’s Soup with yam and lotus decoction, the spleen gradually strengthened, with this formula and then add yellow cypress, sand, saxifrage for pills, slippery sperm healed, and finally take the seeds of sperm pill and get a son. In addition, in case 7, she had diarrhea on the fifth day of the month without a son. She first took Si Shen Wan with Ginseng, Mu Xiang and Sha Ren to warm the spleen and stop the diarrhea, and then took Boneset Pill and Bao Jing Wan to obtain a son. And Yue’s prescription also contains a special “kidney, spleen and beneficial seed decoction” (Fu Ling, Chinese wolfberry, Shengdi, Medlar, Ginseng, Chen Pi, Atractylodes), and analysis: “cover the spirit of blood, all spleen earth is born. This formula to get the seeds of the rest of the yuan, the most rapid production of sperm, Yang thing easy to lift, if you can abstain from sex, the birth of children more easily. This is a miraculous formula.” This fully reflects Yue’s academic thought that the spleen should be taken care of first to produce sperm seeds. The kidney is the master of water and the reservoir of essence, while the heart is the master of fire and the reservoir of spirit. The kidney water should be up to the heart fire, the heart fire should be down to the kidney water, so that the heart and kidney intersect, the water and fire both help, the heart and mind peace, the kidney essence quiet, the discharge of the time, so that the seeds can yulin. As Zhang Jingyue said: “from the kidney and the heart, the kidney first and then the heart, to water to fire, the nature, the nature is the main gas is rising, and the hundred veins together to, this is the true opportunity of fertilization” (Jing Yue Quanshu? Women’s rules? The class of offspring? Yilin policy? The ten machines”). Yue’s also cloud: “The seeds are precious to the sufficiency of kidney water, and especially precious to the tranquility of the heart fire. The present difficult heir, are blamed on the kidney water water enough, but not blame on the heart fire of peace, why? The heart is the ruling fire, the kidneys are the phase fire, and the phase fire follows the orders of the ruling fire, so the childless, although the disease is in the kidneys, but the blame lies in the heart. For example, case 2, young sheep epilepsy, strong slippage, childless, repeatedly used to remove phlegm, consolidate the essence of the astringent agent, sheep epilepsy slippage frequently. Yue thinks: “If epilepsy does not go, the food is turned into phlegm, and the body is not protected for a long time, how can we hope to get a child?” Therefore, when epilepsy occurs, the pill will be opened with bamboo leach, and when the epilepsy will stop, the medicine will be poured down, and after awakening, the decoction of three seeds (suzi, white mustard seed, leek) will be taken. After half a year of abstinence, he often took An Shen Wan, and then took Heart and Kidney Seed Pill and got a son. Another case 8, a scholar with a love of reading and suffering from dream emission and spermatorrhea, 36 years old and still childless. He was 36 years old and still had no son. Yue examined his pulse, which showed that the heart fire was strong and the lower part was weak, and concluded that the heart and kidneys were not intertwined. He first established a decoction formula to calm the heart and mind and benefit the kidneys, and then established a pill formula to tonify the kidneys and consolidate the essence and calm the heart, and took them in turn. After recovering from the disease, he took the Heart and Kidney Seed Pill and got a son. In summary, Yue’s prescriptions listed in the Heart and Kidney Seed Pills, Guangsi Euiji Pills, Heart and Kidney Pills, and Pao Lu Seed Immortal Formula are all treated from the heart and kidneys, fully reflecting Yue’s seeds for heir to the heart and kidneys with the characteristics of medicine. 5, fixing the seeds of sperm avoid sticky and astringent “Su Wen? The upper ancient heavenly truths” cloud: “the husband …… two eight, kidney gas, the day sebum to, essence overflow diarrhea, Yin and Yang, so can have children.” The book emphasizes that men can have children when they have enough sperm, and the representative prescriptions for treating ejaculation are Golden Lock Si Xian Dan (lotus pistil, stone lotus seed, gorgonian, gold cherry seed), the miraculous formula for producing sperm seeds (Tribulus terrestris, Chuan Xian Gong, cuscuta, dogwood, gorgonian, lotus seed, raspberry, wolfberry), and Qian Jin Seed Dan (Tribulus terrestris, lotus seed, dogwood, raspberry, gold cherry, gorgonian). From the medicine used in the formula, we can see that they are all based on tonifying the kidney and fixing sperm, with the discretion of the sequestra, cuscuta, wolfberry, dogwood, etc. to nourish the liver and kidney, and receive the effect of both the symptoms and the root. However, the seeds of sperm fixing formula is different from the general astringent sperm stopping formula, although all use astringent products, but the seeds of sperm fixing is based on tonifying the kidneys and collecting astringency, avoiding the use of dragon bones, oysters of sticky astringency to prevent incomplete sperm application and affect conception, the entire 33 prescriptions of the book only one side of Yan Ling Gu Bao Dan with dragon bones. Yue pointed out that: “the seed of the law, to fix the essence, and astringent medicine, especially the seed of avoid, such as dragon bones, oysters and other flavors, can be entered into the treatment of deficiency, not into the seed of the party. To astringent is not full of sperm, not for those seeking an heir.” Because “oyster, dragon bones astringent sticky stomach, more to take for a long time, every brew into the stasis of heat. Even at the time of intercourse, also worry about sperm incomplete.” It points out the subtle difference between “fixing sperm” and “astringent sperm”. Yue’s sperm fixing seeds, in addition to the above-mentioned kidney and sperm fixing medicine, also like to use seal the marrow Dan (yellow cypress, sand nuts), as in case 6, three years of infertility, hunger and labor slippery sperm, coital sperm thin and little. The diagnosis was that the spleen and kidney were both deficient. First, he took a decoction of Si Jun Zi Tang with yam and lotus meat, and his spleen became stronger. In the process of fixing sperm usually avoid taking seeping carpenter seeds, but if the medicine has not ejaculation, before intercourse can be decoction of carpenter seeds to send solid sperm seeds formula as a guide, to help sperm into pregnancy. Yue’s cube of the wonderful so. 6, Yulin’s formula should be slow figure infertility, the disease is long, the treatment of drugs need to take time, not in a day and night to get results. Look at Yue’s prescriptions for the heir to Yulin, most of them are intended to be slow, that is, Yue’s words: “in the male is used in the neutral agent, to strengthen the true yin, as a lasting plan.” Therefore, Yue’s prescriptions are precious and mild, avoiding cold and hot agents. Cloud: “Although the kidney is water, should not be too cold, the essence of cold is difficult to become pregnant, such as the cold of heaven and earth, the grass will not sprout”; “dedicated to hot drugs, in vain to take hyperactive Yang with the matter, fast momentary pleasure, long and the essence of blood dissipation, the disaster is unpredictable”. This is why the first of the attached formula is Zhonghe Seed Pill, which is intended to be here. The characteristics of Yue’s seed formula are often a combination of cold and heat, moistening and drying, taking into account both the symptoms and the root cause, nourishing yin with warming yang medicine to seek yin in yang, and helping yang with nourishing yin medicine to seek yang in yin, complementing each other. In terms of dosage form, among the 30 internal prescriptions listed, there are 27 pills, 2 wines and 1 soup. “Compared with tonics, pills have the advantages of slow absorption, long-lasting effect, saving herbs, and easy to carry and take, which is very suitable for chronic diseases like infertility. From the causes of infertility discussed in the book, men’s infertility is mostly due to clear semen, thin semen, little semen, spermatorrhea, slippage and impotence. Modern research has shown that the entire process of human spermatozoa from genesis to maturation takes about 76 d [1]. Therefore, the treatment of infertility due to spermatogenesis disorders usually lasts for about 3 months, so the use of mild pills for slow treatment is very appropriate. 7, the seeds do not waste external treatment method Yue’s in the importance of internal medicine to regulate the treatment of infertility at the same time, but also does not waste external treatment method. In the Qing Dynasty, Wu Shiji pointed out in the “Li Bo Era” that “the theory of external treatment is the theory of internal treatment, and the medicine of external treatment is also the medicine of internal treatment, the only difference is the method.” Yue was inspired by the use of “moxa fire for the umbilical cord of newborn babies to strengthen the umbilical cord externally and preserve the vital energy internally so that the true energy does not leak out”. He believes that “adults because of the seven emotions and six desires of the temptation, sound and color, taste and sense of communication, the vital energy gradually misbehaved, the true essence of the gradual destruction. To middle age and gas exhaustion, disease invasion, or difficulty in childbirth, or the death of its natural years, all because the Dantian Qi sea of injury, no nourishing nourishing the good method. Thinking back to the first birth of smoked umbilical solidity, can get but disease regeneration, seeds to prolong the life of the secret.” So the establishment of the umbilical cord to prolong the age of the seed formula, and said that this formula from a different person, unless you meet the soul, can not be lightly taught. The book describes in detail the specific method of smoked umbilical cord, and praised: “moxibustion can make all the veins and smooth, hair orifices are open. The book describes the specific method of smoking the umbilicus, and praises: “When the moxibustion can make all the veins smooth, all the orifices are open. For men with deficiency of the lower yuan, spermatorrhea, lumbar weakness, impotence, and childlessness in middle age, all their diseases are removed. For women with irregular menstrual letters, red and white bandages, cold uterus and long-standing failure to conceive, it can definitely achieve pregnancy. It is really an immortal formula to help the world, and a wonderful method to prolong the life of the heir.” In addition, it also contains Jiu Pin Fu Yang San, which is used to treat impotence in men, who are unable to have a child every time they fail to perform. Yue’s method of external treatment of seeds is worthy of emulation and further study by future generations. In summary, Yue’s treatment of male infertility emphasized the nourishment of sperm as the proper way to seek heirs, and under the guidance of the principle of treating with evidence and selecting prescriptions according to the evidence, the use of medicine attached importance to regulating the spleen and helping transportation to nourish the innate sperm, regulating the heart and kidneys to gather sperm seeds, cautiously using sticky and astringent products to nourish the kidneys and fix sperm, and the prescription of Yulin should be used slowly and slowly. These experiences and features of Yue’s practice are of great relevance to the present-day treatment of male infertility.