There are many clinical manifestations that can cause thick sputum in the morning, such as lung abscess, bronchiectasis, severe pneumonia, etc. Therefore, when a patient has the above clinical manifestations, he or she needs to actively seek medical attention, improve the relevant examination and make a clear diagnosis. If the patient has the above clinical manifestations due to bacterial infection, he or she needs to be treated with antibiotics, such as cefixime, amoxicillin, azithromycin, levofloxacin, etc. If oral antibiotics are not effective, or if the condition is serious, intravenous antibiotics can be used for treatment, such as cefodizime, cefazolin pentahydrate, cefoperazone sodium sulbactam, cefothiamidine, etc. At the same time, sputum culture examination can be improved and antibiotics can be changed experimentally according to the drug sensitivity results. When patients have sputum that cannot be coughed up, they can use expectorant drugs, such as tranylcypromine, eucalyptus pinene, acetylcysteine, etc.