Some patients are asked by the hospital to stop their medication before the EEG test, but some patients are not allowed to stop their medication. Whether epileptic patients should stop their medication before having an EEG test is a question that many patients and primary care doctors are concerned about. Many epilepsy patients or their family members think that only after stopping the medication can the examination reflect the brain electrophysiological activity correctly and record whether there is epileptiform discharge or not, and there are also some patients who are worried that the condition will be aggravated after stopping the medication. In fact, if the drug is stopped briefly before the EEG and other tests, it can indeed reflect the bioelectrical activity of brain cells more objectively, thus helping to improve the diagnostic positivity rate of the EEG and other test methods. However, stopping medication before the examination has the possibility of inducing grand mal seizures, which is especially dangerous for pediatric patients. Therefore, clinical practice should not put patients at risk simply for the sake of a higher positive rate, even though in many cases this risk is only potential and does not necessarily occur. As one of the important objective indicators for the diagnosis of epilepsy, EEG is critical, but the role of EEG must be properly understood and recognized. You cannot diagnose epilepsy just because the word “abnormal” is written on the EEG report form. This is because if the EEG shows only general non-specific abnormalities, such as increased slow waves, mild asymmetry, poor regulation, etc., it cannot be used as a basis for diagnosing epilepsy. Only the presence of epileptiform discharges (spikes, sharp waves, spiking slow waves, spiking slow waves, multiple spiking slow waves, paroxysmal high-amplitude slow waves protruding from the normal background, etc.) is of greater diagnostic significance. In addition, it should be noted that the rhythmic high-amplitude slow waves that occur during hyperventilation in pediatric patients cannot be considered abnormal. He reminded that 0.3% to 3% of the normal population have epileptiform discharges on the EEG but do not have seizures; and there are some epileptic patients who have normal EEG during the interictal period, so epilepsy cannot be excluded because of a normal EEG. Epilepsy, as one of the many neurological disorders that can be treated, is important to be diagnosed in a timely and definitive manner, which is why many primary care physicians are very concerned about how to increase the positive rate of epilepsy EEGs. Experts believe that 24-hour EEG recorders, video and EEG synchronized monitoring, etc. (but if seizures are infrequent, doing such tests is of little significance to the diagnosis) can make up for the shortcomings of the EEG test, but it is more practical to use the existing equipment to improve the positive rate. The positive rate will be improved if it is done in accordance with the formal operational requirements, such as examination time of at least 20-30 minutes, careful performance of various evoked tests (hyperventilation, flashing lights, sounds), and the establishment of a system of evening examination of the EEG in order to record the sleep EEG waveforms. In addition, topographic brain mapping cannot recognize the waveforms (spikes and slow spikes) and phases (positive or negative) of the EEG, so it cannot be used as a basis for diagnosis.CT and MRI can detect any abnormalities in the brain structure, as well as help to search for the cause of epilepsy, but the diagnosis of epilepsy cannot be confirmed or denied on the basis of the presence of abnormalities in the CT or MRI. Therefore, in order to diagnose epilepsy, it is best to have 24-hour video EEG monitoring, so as to diagnose epilepsy more accurately and lay the foundation for future targeted treatment.