When examining poor building syndrome it is important to note the patient’s symptoms, occupational history, and environmental circumstances including work hours and home environment. The main features are basic personal information, symptomatology, description of the work process and indoor environment, ventilation, exposure sources, dust, humidity, temperature and light, whether there are any changes in the environment such as new renovations, new equipment, or other relevant changes, colleagues with the same symptoms and symptoms that can improve after leaving the building. In addition, the examination of poor building syndrome can start from the examination of the primary disease or can be combined with the hospital to get the conventional examination methods, such as routine blood test, sputum test, pulmonary function test, blood gas analysis test, X-ray and other tests. Except for the general examination, the results of all other examinations showed that the scores of all factors for residents of households with excessive pollutants were higher than those of non-exceeding households, and the differences in the number of positive items were statistically significant, revealing that indoor air pollution also has an impact on the mental health of the population. Although the inevitable relationship between the two needs to be further examined, on the one hand, indoor air pollution can cause a variety of “adverse building syndrome”, which in turn leads to individual mental health problems; on the other hand, organic solvents are neurotoxic, and their early, low-dose effects can be manifested as neurological and psychological behavior changes. Organic solvent mixtures also have a certain impact on the psychological state of workers, therefore, indoor air pollution will have a certain impact on the mental health of residents.