OBJECTIVE: To treat large intra-airway tumors or polyps using an electric coiler combined with CO2 freezing, and to investigate their efficacy and safety. DATA AND METHODS: Seventy-seven patients with large intra-airway tumors or polyps (70 malignant tumors and 7 benign lesions) were treated under rigid microscopic guidance in combination with electronic bronchoscopy using an electric trap combined with CO2 freezing. RESULTS: Seventy-seven patients underwent 85 treatments with the electric trap. The lesions were located in 42.9% of the right bronchus, 38.3% of the main bronchus and 21.4% of the left bronchus, and a few were located in subsegmental bronchial openings. The mixed type of malignant tumor accounted for 89.7%, while the pure endotracheal type only accounted for 10.3%. About 4/5 of the patients had endotracheal occlusion before the treatment with the collaterals and about 1/5 after the operation; KPS and shortness of breath index were significantly improved after the treatment. No complications such as hemorrhage or perforation occurred. Conclusion: The treatment of intra-airway tumors or polyps with electric trap combined with CO2 freezing is safe, effective and rapid.