The best time to test for blood uric acid is early in the morning and blood should be drawn on an empty stomach. Uric acid is produced by cell metabolic breakdown of nucleic acids, purines in food and other purine compounds by enzyme metabolism, uric acid metabolism disorders may lead to hyperuricemia, the test of blood uric acid should be performed early in the morning on an empty stomach, in addition, the test should be fasted for 3 days before the test of high-purine foods, the day before the test should be a light diet, should be prohibited from eating and drinking after 10 o’clock, do not drink alcohol, smoking. Under normal circumstances, the reference range of serum uric acid for adult males is 150~416 μmol/L, and the reference range of serum uric acid for adult females is 89~357 μmol/L. Elevation is mainly seen in gout, hemophilia, renal hypoplasia and other diseases, and lowering is mainly seen in chronic cadmium toxicity or genetic defects such as purine oxidase and purine nucleoside phosphorylase. It is recommended that patients who need to test blood uric acid should go to the endocrinology department or rheumatology department of regular hospitals for detailed consultation, and follow the doctor’s instructions for treatment when abnormalities are found.