Large mouthfuls of air produce pain in the heart, usually caused by exudative pleurisy. Most cases of exudative pleurisy are acute in onset, with the main clinical manifestations being chest pain, cough, chest tightness, shortness of breath, and sometimes dyspnea and fever. In mild cases, there are no symptoms, and pleurisy of different etiologies may be accompanied by clinical manifestations of the corresponding disease. Pleuritic pain is the most common symptom of pleurisy, usually located around the heart, often occurring suddenly and varying widely in intensity. It can be a severe stabbing pain that is inconspicuous and ill-defined, or it may be most likely to occur with breathing, or it may persist and be exacerbated by deep breathing or violent coughing, sometimes manifesting as a pulling pain in the abdomen, neck, and shoulders. Pleural friction sounds can be heard on examination, which is the basic condition of pleurisy.