Applied Botox is effective in wrinkle reduction, but the results are usually not obvious. The main ingredient of applied Botox is molecular peptide, which can promote the production of collagen, elastic fibers and hyaluronic acid to hydrate, tighten and reduce fine lines. However, due to the barrier effect of the skin, the amount of Botox that can reach the site of action is often limited, so its wrinkle reduction effect is usually not obvious. The advantages of applicator Botox are that it is simple, non-invasive, relatively safe, and can be applied directly to the skin to improve the appearance of headlines, fine lines around the eyes, and crow’s feet, as well as to restore collagen activity and elasticity, thereby tightening sagging skin and reducing the appearance of wrinkles. For minor wrinkles, this can be alleviated by applying Botox, but for more pronounced wrinkles, satisfactory results are usually not achieved. If you want to achieve obvious anti-wrinkle effect, clinically most use the method of botulinum toxin injection, through the injection of drugs to selectively block the excitation transmission of the nerve-muscle junction, to achieve the effect of relaxing the muscles and removing wrinkles, for the effect of wrinkle removal on the Sichuan lines between the eyebrows, the crow’s feet at the corners of the eyes, the decree lines on both sides of the mouth and nose, neck lines, etc.. However, the action time is limited, and usually need to repeat the injection once in about 4 months. In addition, there are also methods of wrinkle removal such as hyaluronic acid filling and laser treatment. In short, medical beauty methods can effectively remove wrinkles, you should go to a regular hospital to prevent adverse reactions.