Recently, the Department of Cardiovascular Medicine of our hospital successfully installed a single-chamber pacemaker with the septum of the right ventricular inflow tract as the pacing point for a patient with third-degree atrioventricular block, which is the first case in Nanyang City. The patient, Shan Mou, a 78-year-old woman, was admitted to the hospital with episodic syncope, and was diagnosed with arrhythmia, third-degree AV block, and class III cardiac function. Considering the patient’s cardiac function and her family’s financial situation, the department decided to install a single-chamber pacemaker with the right ventricular inflow tract septum as the pacing point after the department’s preoperative discussion. Under the careful arrangement and organization of the department chiefs Han Xuehua and Li Zang, the head nurse Guo Hua, and the cooperation of the whole department, the operation was successful after more than one hour, and the patient has been discharged from the hospital after recovering from the disease. Normal ventricular excitation sequence is a prerequisite for maintaining ventricular systolic and diastolic function. Conventional pacing electrodes are easily and firmly fixed in the apical part of the right ventricle and are widely accepted, but the serious drawbacks are: the normal sequence of ventricular excitation is altered, and the electrical impulses are transmitted retrogradely from the apical part of the ventricle to the interventricular septum, resulting in the formation of the left ventricular myocardium and the left and right ventricles out of synchronization; the septum, the apical part of the ventricle and the posterior wall of the left ventricle are in an anomalous motion, which causes the entire cardiac contraction asynchrony, the loss of the overall coordination and the reduction of ventricular compliance, which is detrimental to the ventricular function. Ventricular compliance is reduced, with multiple adverse effects on hemodynamics and cardiac function. This is more pronounced in patients with borderline cardiac function. Right ventricular inflow tract septal pacing achieves a more favorable hemodynamic state by maximally maintaining the normal ventricular excitation sequence and biventricular synchrony, and can avoid or mitigate the deterioration of cardiac systolic and diastolic function caused by conventional right ventricular apical pacing. It is especially suitable for patients who have symptoms of heart failure or potential cardiac dysfunction but cannot afford the cost of a dual-chamber or triple-chamber pacemaker.