Recently, I encountered several special cases, and I couldn’t help but feel my heart tighten: one: a doctor’s father, recently cervical spine pain, routine radiography did not see obvious abnormalities, after a long investigation without success, further cervical CT tomography, surprised to find: multiple vertebral bone destruction, multiple cervical metastases. Second: Old Li, 69 years old, had back pain for more than a month and had been to the hospital, but no cause of back pain was found. After admission, a chest radiograph was taken: right upper lung 3×5 cm size occupancy, diagnosed as: right upper lung tumor, then further examination of lumbar spine, CT scan was found to be: 4th lumbar spine metastasis, which was the cause of lumbar pain. This time the doctor suggested a radiographic examination to find out that it turned out to be a metastasis in the pelvis, a metastasis in the right femur, and further examination revealed the presence of a tumor in the lung with extensive metastasis. These patients suffered from different tumors, but they did not show much in their normal life, but only showed pain. So, how far is the tumor disease from us? The above patients are all metastatic bone tumors, which are generally malignant tumors; they are secondary to tumors in other parts of the body and metastasize to the bone through various ways and continue to grow in the bone to form sub-tumors. The primary tumor is clearly diagnosed and metastasized to bone after treatment is generally easier to detect, but the primary tumor site and symptoms are hidden, and when metastatic bone tumor is taken as the main complaint for consultation, it is often easy to be confused in diagnosis, and even metastatic bone tumor is taken as other diseases for diagnosis and treatment. However, bones in our body are one of the three most common sites of metastasis for tumors, so metastatic bone tumors account for a significant proportion of cancer patients. It should draw our attention, especially the elderly. Reminder: Many people who have tumors do not have obvious changes in the early stage, so it is easy to be neglected, but generally speaking, tumors will always reveal “traces”, often there may be more weight loss in a short period of time, if the tumor has bone metastasis, there may be long-term unexplained pain, or the site of the tumor can be felt as a mass. If the tumor has bone metastasis, there may be long-term unexplained pain, or the area with tumor can be felt as a mass (not absolutely), and some such as lung cancer or respiratory system may cough up blood, and digestive tract may have blood in the stool. However, these are not absolute criteria for tumor diagnosis, when these changes occur, the public should be alert and should go to hospital for further examination. The only gold standard for tumor is pathological examination, clinically there are blood tests or CT, MR, which are more helpful for early diagnosis, and the specific one depends on the location of your tumor.