She was admitted to the Department of Internal Medicine in 2010 with “epigastric distention with black stool, weight loss for 6 months, dizziness and weakness for half a month”. On examination, she was found to have severe anemia, a right adnexal cyst, a colonoscopy with a clear occupancy of the splenic flexure of the colon, and a biopsy confirming adenocarcinoma. After preoperative preparation, a laparoscopic laparotomy, radical treatment of transverse colonic splenic flexure carcinoma, and debulking of right ovarian cyst were performed on 2012-03-01 under general anesthesia in conjunction with the Department of Gynecology. There was no obvious metastasis in the liver and pelvic floor on laparoscopic exploration, but a hard mass in the transverse colon near the splenic flexure, which had involved the plasma membrane and invaded the nearby omentum, was obviously adherent to the subsplenium and was about 8*5 cm in size. Because of a 6*4 cm cyst in the right ovary, a gynecologist was asked to perform laparoscopic debulking of the right ovarian cyst, and the operation was successful. The patient recovered well after the operation and completed one cycle of chemotherapy and was discharged as scheduled. Postoperative pathology: ulcerated adenocarcinoma of the splenic flexure of the colon with no cancer metastasis in the lymph nodes (0/33). The right ovarian cyst was consistent with an endometrial cyst with focal calcification.? The choice of lumpectomy for both lesions in this case particularly reflects the minimally invasive advantage of lumpectomy.