Acute fatty liver in pregnancy, also known as idiopathic fatty liver in pregnancy, is a serious complication that occurs in late pregnancy. It is a serious complication that occurs in late pregnancy. It has an acute and dangerous onset and has a high maternal and infant mortality rate if the early presentation is not recognized and the diagnosis is delayed. The cause of the disease is unknown, but since acute fatty liver disease in pregnancy occurs mostly in late pregnancy and can only be cured if the pregnancy is terminated, it is presumed to be related to hormonal changes caused by pregnancy. The lesion is caused by the accumulation of free fatty acids in liver cells and organs such as kidney, pancreas and brain, resulting in multi-organ damage. The disease mostly occurs between 28 and 40 weeks of gestation, especially in first-time mothers around 35 weeks of gestation, and is more common in gestational hypertensive disorders, twin pregnancies and male fetuses. At the beginning of the disease, there is only persistent nausea, vomiting, weakness, epigastric pain or headache and other discomfort, which can be easily confused with gastroenteritis, liver disease and other digestive system diseases. If the pregnancy is not terminated, the disease progresses rapidly, with coagulation disorders (such as skin petechiae, petechiae, vomiting blood, blood in the stool, gingival bleeding and intracranial hemorrhage), hypoglycemia, impaired consciousness, psychiatric symptoms and coma, oliguria and anuria, and death often occurs within a short period of time. The prognosis of this disease is closely related to the early and late treatment, and the maternal and infant mortality rates are extremely high with conservative treatment, and there is no precedent of prenatal recovery in the world so far. Therefore, once the diagnosis is confirmed or highly suspected, the pregnancy should be terminated as soon as possible, regardless of the severity of the disease and its early or late stage. If the pregnancy is terminated early, the liver function of most patients recovers rapidly after delivery, but if the pregnancy is diagnosed late and not terminated in time, it has developed to the stage of multiple organ failure such as severe coagulation dysfunction, and the patient often dies from total gastrointestinal hemorrhage, generalized subcutaneous petechial hemorrhage or even intracranial hemorrhage.