Fatty liver and liver cancer

  Can fatty liver cause liver cancer? With the improvement of people’s living standard, the incidence of fatty liver is gradually increasing. More and more people are worried about whether fatty liver can turn into liver cirrhosis. Can fatty liver promote the formation of cancer?  Can fatty liver cause liver cancer?  Under normal circumstances, the liver maintains a dynamic balance between the decomposition, synthesis and detoxification of substances in the body and the metabolism of fats. The normal liver contains a small amount of fat, which is about 4%-5% of the weight of the liver. If too much fat accumulates in the liver, exceeding 10% or even 15% of the liver weight, then it is called fatty liver. Fatty liver can generally be divided into two types: acute and chronic. Acute fatty liver is similar to acute and subacute viral hepatitis, it is rare, clinical symptoms are fatigue, nausea, vomiting and varying degrees of yellowing, and liver coma and kidney failure can occur in a short period of time, serious cases can die from complications within a few hours, if treated in time, the condition can rapidly improve in a short period of time. Nearly 60% of chronic alcoholics develop fatty liver, and 20-30% will eventually develop cirrhosis. The incidence of liver fibrosis in non-alcoholic fatty liver is 25%, while the probability of cirrhosis is lower and the development process is relatively slow, with 1.5%-8.0% of patients progressing to cirrhosis. Chronic fatty liver disease is more common, with a slow, insidious onset and a long course. Some patients may have loss of appetite, nausea, fatigue, pain in the liver area, abdominal distension, and a feeling of fullness and pressure in the right upper abdomen. Because these symptoms are not specific and are similar to chronic gastritis and cholecystitis, they are often misdiagnosed and mistreated.  Fatty liver is an early manifestation of various kinds of hepatotoxic damage, but fatty liver disease itself is not directly related to the occurrence of primary liver cancer, and fatty liver is not a risk factor for liver cancer, but certain causes of fatty liver, such as alcohol consumption, malnutrition, drug and toxic substance damage, are both factors in the development of fatty liver and liver cancer. In countries with low prevalence of hepatitis virus infection, cirrhosis caused by long-term alcoholism is an important factor in liver cancer, and about 2-3% of chronic alcoholics develop liver cancer through alcoholic cirrhosis. In China, alcoholic cirrhosis combined with liver cancer is almost always accompanied by hepatitis B virus and/or hepatitis C virus infection, and the incidence of liver cancer is high in those with coexisting alcoholism and chronic viral hepatitis, with earlier age of onset and shorter life expectancy. Non-alcoholic fatty liver disease has a low incidence of cirrhosis, which occurs later, and therefore liver cancer is rare. Therefore, to stay away from alcohol is to stay away from fatty liver, which is to stay away from liver cancer. Fatty liver is mainly a disease caused by poor lifestyle, therefore, in principle, the treatment is based on correcting poor lifestyle and gradually reversing fatty liver. For those with severe symptoms, treatment with liver-protecting, lipid-removing and anti-fibrotic drugs is necessary.