The patient was admitted to the hospital with “skin stiffness for one year, aggravated for more than three months”. In the winter of 2005, the patient developed skin tightness on both hands without any obvious cause and had difficulty in making a fist; in 2006, the skin on the upper limbs became hard and the arms could not be straightened. He had a feeling of tightness in the skin of the extremities, could not be picked up by hand, was weak, had no facial color, was short of breath, had poor appetite, had average sleep at night, had clear urine, had a purple tongue and thin pulse. Physical examination: cardiopulmonary auscultation (-). The skin at the end of the finger was diffusely swollen and hardened, and could not be pinched by hand, the skin lines disappeared, and the finger ends were cyanotic. Ancillary tests: immuno-eight: IgG: 16.20g/l, RF: 86.00U/ml, ANA antibody profile: anti-Scl-70(+). Western medicine diagnosis: scleroderma, Chinese medicine diagnosis of lung deficiency and blood stasis in dermatological paralysis, the treatment is to tonify the lung and clear blood stasis, warming the meridians and opening the veins, with tonic lung soup: Radix Codonopsis pilosulae 30g, Radix Astragali 30g, Radix Angelicae Sinensis 12g, Rhizoma Yam 12g, Fructus Schisandrae 10g, Salviae Miltiorrhizae 20g, Flos Daturae 15g, Peach kernel 10g, Safflower 10g, Gui Zhi 10g, Scorpion 10g, Radix Platycodon grandis After 21 doses, the symptoms of skin tautness and shortness of breath were significantly reduced, and the skin swelling of the fingers disappeared and the cyanosis of the finger ends was reduced after 6 months of taking the formula with additional reduction. The lung is the master of qi and the master of the surface of the body. The lung is responsible for nourishing the skin and has a governing and regulating effect, and is in harmony with the mechanism of the heart, and when the qi moves, the blood moves, thus allowing the circulation of blood vessels around the body. “The physiological function of the lung is normal, the skin is dense, the hair is lustrous, and the ability to resist external attacks is strong; on the other hand, if the lung is deficient, the physiological function of propagating the body qi and transferring essence to the skin is reduced, the body surface is not solid, and the ability to resist external attacks is low, and there can be excessive sweating and easy to catch a cold, or the skin and hair are emaciated. This can lead to excessive sweating and colds, or haggard and withered skin. The deficiency of lung qi cannot promote blood flow, resulting in loss of blood flow and astringent pulse pathways, which can be seen as white and blue extremities, sclerosis of the skin around the body, dull brown skin tone, bruised finger (toe) ends, petechiae or purple tongue, and thin and astringent pulse. Therefore, lung deficiency is the main cause of this disease. When the lung is deficient, it is unable to push the blood to run, and the blood loses its fluidity and the veins become astringent and stagnant, which leads to blood stasis. Therefore, it is proposed to treat scleroderma by tonifying the lung and clearing stasis, which can not only improve microcirculation and increase blood flow, but also improve the hypoxic state of organ tissues, thus achieving the purpose of treating scleroderma. The selected formula is derived from the Tonic Lung Soup of the Yongxing Bell Formula. It is based on Radix Codonopsis, Radix Astragali, Radix Angelicae Sinensis, Rhizoma Yam, Fructus Schisandrae, Radix Salviae Miltiorrhizae and Flos Daturae. Radix et Rhizoma Ginseng and Radix Astragali are the key medicines to tonify lung qi; yam is sweet in taste and flat in nature, and has the function of tonifying lung, spleen and kidney qi. It is used in conjunction with Radix Codonopsis, Radix Astragali and Rhizoma Polygonati, to tonify the qi of the internal organs and meridians and to keep the qi of the internal organs in good harmony. The patient was admitted to the hospital with “dry mouth and eyes for one year and recurrent low-grade fever for more than four months”. One year ago, the patient had dry mouth and eyes with no obvious cause, accompanied by dry throat, astringent eyes and blurred vision, but no attention and treatment were given. In the past 4 months, dry mouth and eyes worsened, accompanied by recurrent low fever, fatigue, hot flashes and night sweats, feeling hot in the heart of the hands and feet, aching pains in both lower limbs, with pains in both knees obvious, occasional dizziness, sleepiness, normal urine, dry stools, one line in 2-3 days, red tongue without fluid, cracked without moss, weak and slightly counted pulse. Investigation: anti-SSA antibody (+), anti-nuclear antibody quantification >500U/mL, ophthalmological examination: consistent with dry eye. Western medicine diagnosis: dry syndrome, Chinese medicine identification of the disease and evidence for dryness of Yin deficiency of internal dryness. The treatment is to nourish yin and produce fluid, clear heat and moisten dryness, and choose our homemade “Jin and Blood” granules to take orally, and after one month, the patient’s dry mouth and eyes symptoms basically disappeared. The formula of our homemade “Jin and Blood Source” is based on Yuquan Pill from “Miscellaneous Diseases Source and Stream of Rhinoceros” and Yuquan Tang from “Medicine Kezhong Ginseng and Xilu”. The formula is composed of Sheng Di Huang, Nan Sha Shen, Mai Dong, Lu Guan Cao, Red Peony, Wu Mei, Shui Niu Jiao, Tu Fu Ling, Herb Snake, Wei Ling Xian, etc. together to nourish Yin and generate fluid, detoxify and clear dryness. Therefore, the water hyacinth, red peony, Fu Ling clear heat and cool the blood to detoxify the blood, promote the excretion of endotoxins, keep the glands open, avoid repeated absorption of endotoxins aggravate the damage to internal organs; herb snake, Wei Ling Xian, deer artichoke good at dispelling wind and dampness, search for wind toxins, pass the pain.