In recent years, numerous genetic studies have shown that epilepsy is indeed a genetic disorder, including both primary and secondary epilepsy. Genetics is the primary endogenous cause of epilepsy, while all aspects of brain damage from embryonic onset to pre-onset are the primary exogenous causes of epilepsy. Studies of twins with epilepsy have shown that children with epilepsy are genetically susceptible, with monozygotic twins having about six times the consistency of dizygotic twins, with significant differences in the consistency of the disease and the consistency of the seizure type. This suggests that the consistency of epilepsy varies with genetic traits, which demonstrates that epilepsy is genetically related. Family analysis and epidemiological surveys of epilepsy patients show that the prevalence of epilepsy in relatives with idiopathic epilepsy is 3.8% to 10.8%, and individually up to 19.8% to 35%, which is significantly higher than that of symptomatic epilepsy (1% to 4.6%), which is much higher than that of the general population (0.3% to 0.6%), and the closer the blood relationship with the patient, the higher the prevalence. It is well documented that no fewer than 10 human epilepsy genes have been localized and that approximately 150 genetic syndromes can be combined with epilepsy or myoclonus. Some secondary epilepsies (e.g., secondary to brain tumors, traumatic brain injury) also have genetic characteristics, and it is more common for relatives to have tumors complicated by epilepsy, even in the absence of seizures. The above data suggest that epilepsy has a certain genetic predisposition. However, this only indicates that people with genetic qualities have a low seizure threshold and an increased susceptibility to seizures when they encounter certain environmental factors, while the onset of seizures is determined by both internal and external factors. The genetic factors that cause seizures in real life only account for a small percentage of all epilepsies (some reports vary from 50% to 20%), so patients should not worry too much about the genetic aspects of epilepsy.