Hives caused by Helicobacter pylori can be determined by laboratory tests and effective treatment with anti-H. pylori therapy. H. pylori is the most important cause of chronic gastritis, gastric ulcers, duodenal ulcers, gastric cancer and other diseases. Urticaria is an allergic skin disease characterized by the appearance of an airy rash on the skin. The etiology of urticaria is complex, and possible causes include drugs, food, various infections, psychiatric factors, and visceral and systemic diseases. Helicobacter pylori infection may be an important factor in a small number of patients. H. pylori infection also requires testing such as the H. pylori breath test. Chronic urticaria clinically suspected to be associated with chronic inflammation may be considered for anti-infective treatment as appropriate when other treatments are ineffective, e.g. anti-Helicobacter pylori treatment has been shown to be effective in urticaria associated with Helicobacter pylori-associated gastritis. If only H. pylori positive, by anti-H. pylori treatment is ineffective, can be negated H. pylori caused urticaria. Due to the complexity and variety of causes of urticaria, please do not take medication on your own, it is recommended to consult a doctor in time for early diagnosis and treatment under the guidance of a professional doctor.