Aspirin has a thromboprophylactic effect. Aspirin can inhibit the production of platelet thromboxane A2, thus inhibiting the aggregation of platelets and playing a thromboprophylactic role. The main mechanism of action is irreversible inhibition of the synthesis of cyclooxygenase, which plays the role of anti-platelet, so it is widely used in the treatment of cardiovascular and cerebrovascular diseases, especially for patients with secondary prevention of cardiovascular and cerebrovascular diseases, and has the effect of inhibiting platelet aggregation and preventing blood clots. Aspirin can reduce the risk of acute myocardial infarction in patients and can prevent the recurrence of myocardial infarction. It also reduces the risk of transient ischemic attacks and secondary strokes, as well as the risk of morbidity in patients with stable and unstable angina. It can also be used to prevent thrombosis after arterial surgery or interventional procedures. In conclusion, aspirin can have a thrombotic preventive effect through its platelet inhibitory effect.