Indications and contraindications for tumor chemotherapy

I. Indications of tumor chemotherapy With the increasing number of antitumor drugs and the improvement of clinical application technology, the indications of chemotherapeutic drugs are also expanding. 1, Radical chemotherapy For chemotherapy-sensitive solid tumors and hematological system tumors. For example, small cell lung cancer, malignant hyperemesis gravidarum, chorionic epithelial carcinoma, testicular seminoma, Hodgkin’s lymphoma, multiple myeloma, leukemia, etc. are sensitive to chemotherapy, and most patients can be cured by chemotherapy alone. 2, adjuvant chemotherapy After surgery or radiotherapy, most patients need adjuvant chemotherapy after surgery or radiotherapy to reduce local recurrence and distant metastasis, except for some solid tumors in early stage. 3, neoadjuvant chemotherapy Neoadjuvant chemotherapy can be used for locally advanced patients to create conditions for surgical treatment, and then select adjuvant chemotherapy according to the pathological type and disease staging after surgery. 4, palliative chemotherapy For advanced cases that cannot or should not be treated with surgery and radiotherapy, according to the general condition of the patient, without contraindications to chemotherapy, single-agent chemotherapy or combination chemotherapy is used to reduce pain, improve the quality of life and prolong the survival time. 5, relief chemotherapy Complications of malignant tumors, such as superior vena cava compression syndrome, respiratory compression, spinal cord compression and metastatic intracranial pressure increase, etc., can also choose chemotherapy first to relieve the compression symptoms as soon as possible. Contraindications to tumor chemotherapy 1. Absolute contraindications End stage of disease, pregnancy, serious infection, coma and other major organ function serious failure. Relative contraindications Old and frail, tumors insensitive to chemotherapy, KPS score less than 40 points (PS score > 2 points), lactating women, infants under 3 months of age, major organ function damage, mental disorders, not easy to cooperate, complications of infection and fever, nutritional disorders and severe anemia, bone marrow metastases, tumors have not been diagnosed by histology or cytology.