It goes without saying that contemporary technology has brought benefits to us humans, leaving footprints of human exploration from the sky to the deep sea. As man touches nature, he also changes it. From the slash-and-burn of the great river basins to the tail flames of the Apollo spacecraft cutting through the sky, if we say that every advancement of mankind is using technology as a weapon to demand more from nature, it is better to say that the civilized side of technology itself makes mankind know how to better learn to be humble in front of nature. Although humans are often cautious and respectful when it comes to such topics, they are always driven by the desire to maximize their own interests and the search for the unknown, and are always making the same mistake of denying that humans are part of nature and “fantasizing” that nature is actually a tool or private property of humans. This “fantasy” is often really a fantasy, and even science fiction writers do not use this idea as the main line of thought in their work. Even science fiction writers do not make this idea the main theme of their work. If people who think this way in science fiction, they are often portrayed as perverted businessmen or science nuts, and their end is often predictable. But in reality, scientific people (I won’t use the term scientist or researcher for now) who think this way or similar thoughts abound, or this kind of thinking exists in a more insidious way in their nature, or even in the nature of all human beings. This being said, “genetic modification” is one such serious topic that we are facing today regarding human beings themselves. I often hear people say about GM that “humans are playing God”. I think we should say this not with the triumphant tone of the pioneers or colonizers, but with some “necessary concern”. In human history, every time we have tried to change nature, the end result has been that we ourselves have been changed, with some benefits and some disasters, in other words, we can see this as the advantages and disadvantages of technology for human beings. For genetic modification, especially for genetically modified food, compared with the past, it may not only change human productivity, production relations, social structure and other such economic structure and superstructure, but most importantly, it may change our basic human being as a living being, who considers himself as “God”. itself. Looking back at the history of genetic modification and genetically modified foods, in 1910, Morgan confirmed that genes were located on chromosomes through his study of the white eye mutation in Drosophila, and in 1953, Waston and Crick revealed the double helix structure of DNA, ushering in a new era of revealing the phenomenon and nature of life at the molecular level. In 1980, Cordon et al. first used microinjection to breed “novel” transgenic mice with an exogenous DNA fragment, the thymidine nucleoside kinase gene. In 1982, Palmiter et al. successfully introduced the human growth hormone gene into the nucleus of a mouse fertilized egg for the first time and obtained a super transgenic “mouse” that integrated and expressed the exogenous DNA. The first human growth hormone gene was introduced into the male nucleus of the fertilized mouse egg and a super transgenic “mouse” was obtained that integrated and expressed this exogenous DNA. Since then, according to the idea and technical line of the injection method to breed transgenic mice, transgenic rabbits, transgenic sheep, transgenic pigs, transgenic fish, transgenic goats, transgenic chickens, etc. In 2000, the global planting of transgenic plants reached 4420 hectares. China’s genetically modified plants are the fourth largest in the world, and the Ministry of Agriculture has approved the planting of the following crops: bell peppers, tomatoes and potatoes; corn and rice are the staple crops. Crops that may be approved one after another in the future are wheat, sweet potatoes, cereals, peanuts, etc. Imported genetically modified foods include soybean oil, rapeseed oil, soybeans, etc. When the vast majority of us still only know the term “genetically modified” from the newspaper news channels and its various levels of awareness more in the follow a variety of “experts say” cloud, “genetically modified The term “genetically modified” has entered our lives with familiar faces such as McDonald’s, KFC, Nestle, Master Kong, Want Want, Wahaha, Yili, etc., as well as a wide range of edible soybean oils that have caught us off guard. Only this way is not “with the wind into the night, the silent”, but “quietly into the village, shooting do not”. Although people understand the importance of “food safety” to be as important as protecting their own lives, and have zero tolerance for excessive additives and microorganisms in food, the public lacks sufficient scientific knowledge of the unknown or potential dangers of “genetic modification”. However, when faced with such an unknown or potential danger as “genetic modification”, the public, lacking sufficient scientific knowledge, appears to be incredibly vulnerable. Leaving aside the question of whether it is the government’s responsibility or the morality of scientists that is at stake, a recent report says that Professor Zhang Chenyu of the School of Life Sciences at Nanjing University has found that some small molecules in plants can enter the human body and may reverse their effects, controlling the body’s genetic activity and affecting the body in a more proactive way. These arrogant little molecules are tiny RNAs, and a paper related to them was published in Cell Research. It seems that our worries have become more justified. Since rice, which has been consumed since our ancestors, can affect us on a genetic level, how many unknown factors in “genetically modified” foods are changing our bodies? Perhaps when we are still smug that scientists can implant a polar bear gene to resist freezing into tomatoes to produce cold-tolerant tomatoes, we do not know that food has been silently “genetically modified” to us. But neither the food nor we know where it is going to “turn” us. Hopefully, our fears and worries will be proven by future technology to be as unfounded as the fears of people when geocentrism was broken. However, the practice of human history has repeatedly proven one of the simplest truths: the ultimate beneficiaries of nature’s compliance are in fact human beings themselves.