For hypertension caused by vascular sclerosis, it can be treated by taking first-line five types of antihypertensive drugs, and at the same time, the combination of anti-platelet aggregation drugs and lipid-lowering drugs can be applied. The first-line antihypertensive drugs that can be taken are calcium channel blockers, such as nifedipine and amlodipine, as well as ACEI drugs, such as captopril and enalapril, and ARB drugs, such as valsartan. In addition, diuretics, such as hydrochlorothiazide, furosemide, etc., should also be taken, which are effective in the treatment of vascular sclerosis type hypertension and can lower blood pressure smoothly. In addition, anti-platelet aggregation drugs such as aspirin, clopidogrel and Tegretol should be applied for vascular sclerosis, and statin lipid-lowering drugs such as atorvastatin calcium tablets and rasulvastatin calcium tablets should be taken regularly. In addition to the combination of the above drugs, you should also visit the hospital regularly to check the degree of vascular sclerosis and whether there are any combined cardiovascular and cerebrovascular comorbidities.