The patient was a 51-year-old female with cough, wheezing and breath-holding for 10 years, with chest tightness and shortness of breath, burning sensation behind the sternum, recurrent episodes without seasonality. He was treated with inhalation medication in the respiratory department to control the symptoms. He visited the GERD center because he learned about GERD in the health lecture, and was diagnosed with GERD after consideration of gastroscopy and impedance tests.