There is a vague pain in the upper part of the stomach at the fossa, usually epigastric pain or pain under the glabella. Patients can first clarify whether they have eaten cold, spicy and other stimulating foods, or recent mental stress and other factors that cause discomfort here due to plant nerve disorders. This condition can be gradually relieved by adjusting the lifestyle, such as maintaining a good mood, keeping warm, and appropriate massage. If the patient has persistent discomfort, it is mostly considered to be caused by diseases, the common ones are as follows: 1. Digestive system diseases: 1. Reflux esophagitis: mainly caused by impaired gastric function, such as decreased anti-reflux function of the stomach, damaged esophageal mucosa, etc. The onset may also cause vague pain in the upper fossa of the stomach, which may also be accompanied by acid reflux, nausea, vomiting, heartburn and other discomfort. Once the above symptoms appear, patients need to seek timely medical attention and take targeted treatment. Common treatment modalities include medication, surgery, such as prokinetic drugs to promote gastric emptying to help reduce esophageal reflux; 2. Gastric and duodenal ulcers: inflammatory lesions of the digestive tract may also cause vague pain in the upper fossa of the stomach, mostly before meals, after eating or during hunger, and may be accompanied by belching, acid reflux, anorexia and other symptoms. The symptoms may be accompanied by belching, acid reflux, anorexia, etc. Most of the clinical treatments are acid-suppressing drugs and gastric mucosa-protecting drugs, such as omeprazole and lansoprazole, etc. 3. The onset of the disease may also cause symptoms such as vague pain in the upper fossa of the stomach, lack of appetite, acid reflux, nausea, etc. The pain may be dull, burning or vague. In this case, patients need to consult a doctor in time, and clinical treatment usually follows the principle of individualization, and different treatment methods are chosen according to different symptoms; 4. Other: such as chronic cholecystitis, chronic pancreatitis, chronic hepatitis, gastric cancer, etc. may also occur in the upper fossa of the stomach, accompanied by skin color changes or other discomfort. Coronary artery disease is a heart disease caused by ischemia and hypoxia of the myocardium due to coronary artery lesions. The typical symptom at the onset is a crushing or suffocating pain in the anterior chest, and sometimes vague pain in the upper fossa of the stomach, accompanied by chest tightness and breath-holding. If the above symptoms appear, you should seek medical treatment in time, and the common clinical treatment methods are drugs, interventions and surgery; 2, angina pectoris: mainly due to myocardial ischemia and insufficient oxygen supply, the onset of the symptoms is pain or pressure in the precordial region, chest, and also vague pain in the upper stomach fossa. It is important to consult a doctor promptly when the above symptoms are detected. 3, Other: such as pericarditis, heart failure, etc. may also appear vague pain in the upper fossa of the stomach. In addition, if the vague pain in the upper fossa of the stomach is caused by pathological factors, it is important to consult a doctor promptly and follow medical advice for treatment according to the cause.